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KMID : 1143620160200010028
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Korean Journal of Nuclear Medicine Technology
2016 Volume.20 No. 1 p.28 ~ p.31
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The Evaluation of External Radiation Exposure dose rate for Radium-223 Dichloride
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Cho Seong-Wook
Yoon Seok-Hwan
Song Jong-Min
Kim Tae-Yeob
Lim Jung-Jin
Kim Jin-Eui
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Abstract
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Purpose : 223Ra-Dichloride is used for the medicine of castration-resistant prostate cancer (CRPC) and which emits α-ray
of 28 Mev that is used for therapy. However 223Ra-Dichloride emits β-ray of 3.6% and γ-ray of
1.1%(80,156,270 keV) aside from α-ray in decay. Therefore we would like to evaluate external radiation expose
dose rate of γ-ray of 223Ra-Dichloride.
Materials and Methods : We calculated external radiation expose dose rate using γ-constant of 223Ra-Dichloride, 99m
Tc based on Health physics(2012). 223Ra-Dichloride of 3.5 M㏃ and 99mTc-MDP of 740 M㏃ were applied. external radiation expose dose rate 15 times from 1m by survey meter.
Results : γ-contant of 223Ra, 99m Tc-MDP from 1m distance based on Health physics(2012) is 0.0469, 0.0215. calculated
value of external radiation expose dose rate was 16 μ㏜, 34 μ㏜ which activity is 223Ra-Dichloride of 3.5 MBq and 99mTc-MDP of 740 M㏃ from 1 m . and measured mean value of 1 m was 0.7 μ㏜/h, 18 μ㏜/h.
Conclusion : γ-constant of 223Ra is higher than 99m Tc based on Health physics(2012). however calculated maximum external radiation expose dose rate of 223Ra-Dichloride is lower than 99mTc due to actually used quantity of activity of 223Ra-Dichloride is small. measured value of 223Ra-Dichloride is also lower than 99mTc-MDP. Therefore external radiation expose dose rate of γ-ray of 223Ra-Dichloride is very low.
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KEYWORD
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223 Ra-Dichloride , external radiation expose dose
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